Aluminum salts, a key ingredient added in growing amounts to numerous childhood and adult vaccines, have never been tested for their effects on health in humans, a new review paper from British researchers says.
“Aluminum based adjuvants are effective and cheap but are they safe?” the team of researchers at Keele University ask in the study published this month in Allergy, Asthma & Clinical Immunology.
Although aluminum has been used for decades as an adjuvant to provoke the immune system to make antibodies to other vaccine ingredients, it works precisely because it is toxic, said Christopher Exley, who has studied the metal’s adverse effects biological systems from fish to humans for more than three decades. His paper with Emma Shardlow and Matthew Mold reviews what is known about the different modes of action of different aluminum salts and confirms that it may account for the wide spectrum of serious adverse events associated with vaccines.
“Aluminium-adjuvanted vaccines have a long history of clinical successes and a commensurately long history of vaccine-related adverse events,” the scientists write. “Since there is no requirement to demonstrate the safety of [aluminum-based adjuvants] ABAs, one could quickly surmise that adverse events following vaccination are the direct or indirect effects of ABAs.”
“What might be the cause of such events, ranging from health issues directly associated with the injection site to brain encephalopathy and death?” Exley asks in a related blog published today in the Hippocratic Post.
“We know that aluminium adjuvants are toxic at the injection site, this toxicity is essentially their mode of action (see https://www.hippocraticpost.com/infection-disease/aluminium-adjuvants-vaccines/), and evidence is burgeoning that this toxicity is also being manifested away from the injection site (see https://www.hippocraticpost.com/infection-disease/aluminium-and-autism/).”
Taking aim at pharmaceutical giant Merck, the manufacturer of Gardasil and Gardasil 9 vaccines against the human papilloma virus (HPV), Exley notes that the company has “prevented any independent study of its proprietary adjuvant and concomitantly this vaccine has arguably the highest frequency of recorded adverse events of all vaccines and this according to the manufacturer’s own data!”
Exley said Merck’s own ‘safety’ trial data is not valid because it compares the vaccine to the company’s proprietary aluminum adjuvant as “placebo” and finds a skyrocketing 2.5 percent adverse event effect in both groups. “So, even though 25000/1,000,000 perfectly healthy recipients become ill on receiving Gardasil it is safe since the same number become ill on only receiving the adjuvant alone,” said Exley. “In a very small true control group where the placebo was reported as saline, there were zero (none) adverse events, enough information in itself to support the toxicity of their proprietary aluminium adjuvant?”
Most aluminum-containing vaccine trials, like those of Gardasil, only test the vaccine against aluminum alone as a placebo or, in some cases, against other aluminum-containing vaccines.
‘Stupidity’ of public health defense
Exley addressed aluminum safety in a sweeping recent interview with reporter Christina England and countered the most common public health defense of aluminum. “One of the great fallacies about human exposure to aluminum from vaccination is people say, ‘Yes, but you know it’s only 500 micrograms, half a milligram of aluminum – that’s just a fraction, for example, of the aluminum that might be in your diet every day and therefore this cannot have any consequence.”
This is the argument offered by leading vaccine inventor and promoter, Paul Offit, a pediatrician with the Children’s Hospital of Philadelphia.
“You know, for anybody who has worked on aluminum for their whole lives, for 35 years,” Exley said, “it just sort of makes me cringe to hear this sort of stupidity because the suggestion that a route of exposure, for example, aluminum in your diet via your gut is identical to a route of exposure when aluminum is injected directly into the muscle and therefore into the bloodstream is just ludicrous and meaningless and shows a complete and utter lack of understanding of biology.”
“Of course, often the people who say this don’t have a complete lack of understanding of biology,” Exley added. “They simply want to try to find some sort of overarching argument against the fact that what they see as a small amount of aluminum in a vaccine could have any possible deleterious effects.”
Exley pointed out that what public health considers a tiny amount of aluminum in a single injection – 500mg/L -- is in fact a “huge concentration” of the toxic metal. A concentration of only 0.2 mg/L of aluminum 2,500 times smaller kills fish in experiments.
The interview also explains that as well as stoking the immune system against viruses and bacteria contained in vaccines, researchers now understand that the immune system can produce antibodies against aluminum itself. “In other words, the body develops a ‘memory’ to aluminum which means that with the next significant exposure to aluminum, the body starts to produce an immune response against that.”
If aluminum is deposited elsewhere in the body, Exley explained, “those other sources and sinks of aluminum also become part of that [inflammatory immune response].”
Numerous exposures to aluminum over a short period of time “raise the possibility of a cascade of events not only at the injection site but around the body and this is, again, a real worry,” he said.
A number of studies in the past five years have demonstrated that the tiny microscopic shards of aluminum adjuvant in vaccines do not stay at the injection site but move in white blood cells to distant sites around the body, including brain, where they remain for as long as the experiments have lasted.
Most recently, studies published this month on vaccines and aluminum adjuvants injected into sheep show that the aluminum transports to lymph nodes and is associated with negative neurological behaviour changes in the animals.
“Burgeoning knowledge regarding the biological activities of [aluminum-based adjuvants] now dictates that their safety should be evaluated independent of their presence in vaccine formulations," the Keele review concludes.